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(0:00) Introduction to Hormone Replacement Therapy (1:47) Testosterone Replacement vs. Optimization (3:19) Benefits of Testosterone Optimization Therapy (6:30) Risks of Testosterone Abuse (7:32) Hormones in Health and Longevity (9:20) Hormone Replacement Therapy for Women (10:35) Key Takeaways and Conclusion00:00:00
Hormone replacement therapy, when done correctly, can be one of the most powerful
00:00:04
tools during perimenopause, menopause, and post menopause.
00:00:09
Symptoms like anxiety, poor sleep, brain fog, weight gain, mood swings, and then the loss of
00:00:15
drive or that identity are not things you just have to live with.
00:00:20
Peter Attia and many longevity focused physicians now openly say HRT is a missing link
00:00:26
for women's health, bone health, and overall long term vitality.
00:00:30
And when used correctly, estrogen supports the brain, progesterone supports sleep and
00:00:38
calmness, reducing of stress.
00:00:41
Testosterone, yes, even in women, supports strength, confidence, and overall metabolism.
00:00:47
Welcome to Health Decoded, your number one source for real health information with your
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host doctor Alessi and Matt Tack.
00:00:58
Welcome to the Health That Decoded podcast.
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This is your host, Matt Tack, and today's episode is gonna be a solo one.
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But I'm excited about it, and we're diving into the topic that is absolutely on fire right now
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in both men's and women's health.
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And that topic is hormone replacement therapy specifically TRT or HRT for women and what we
00:01:21
actually practice in our clinic which is what we actually call TOT, because we want that
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optimization piece to be plugged in, not the replacement.
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So testosterone optimization therapy or hormone optimization therapy, Because let's be honest,
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hormones are everywhere in the conversation right now, which is why I wanted to spend some
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time to dig in a little further.
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Some people swear by them, some people are scared by them, Some people think they're the
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magic bullet, and others think they're just pure dangerous.
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But the truth, like most things in health, there is more nuance to that.
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So today, I wanna cut through the noise and talk about what actually is TRT and HRT, three
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real pros, some two cons that I want you to know about, and when used correctly, it may be
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one of the most powerful tools for longevity, and why women absolutely cannot be left out on
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this conversation.
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This isn't about hype.
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This is about education.
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So let's decode it.
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Replacement versus optimization.
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What does that even mean?
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First, we need to clear something up.
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Most people think TRT means replacing testosterone because you're low.
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That's not how we approach it.
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At our clinic, we focus on replacement.
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We don't focus on replacement, I'm sorry.
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We focus on optimization.
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And that's why we call it TOT, testosterone optimization therapy.
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I think this was actually taglined by Jay Campbell, so I'm going give you a shout out on
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that.
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So here's the difference.
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Replacement says, let's get you barely into the range, so that you can operate.
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Optimization says, let's get you into your best physiological version based on labs, symptoms,
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lifestyle, and overall long term health.
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You know, I always like quoting Peter Itzia.
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He said this, the goal isn't to make testosterone super physiological.
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The goal is to restore function, energy, body composition, and overall resilience.
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And that's the key word, resilience, because testosterone isn't about ego, size, or
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aggression.
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It's about very key components of longevity, which are muscle mass, bone density, metabolic
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health, mood mood and cognition, cardiovascular protection, and yes, just pure longevity.
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So let's dig into the three pros that I have of TOT.
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Let's start with the upside because when this is done right, the benefits can be absolutely
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life changing.
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Number one, lean muscle mass when used correctly, strength and overall metabolic
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health.
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Testosterone is one of the most powerful regulators of lean muscle mass.
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Let's get more specific.
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More muscle means better insulin sensitivity, higher resting metabolism, lower risk of
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diabetes, stronger bones, and just pure better aging as age progresses itself.
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I again want to go back to Peter Ottia.
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I love following what he has to say, and he's very clear on this.
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Muscle mass is one of the strongest predictors of longevity as we age, and therefore
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testosterone supports the one that protects us the most as we get older.
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That is absolutely strength being more powerful in your body.
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So number two: mental health drive cognition, cognitive function.
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Low testosterone doesn't just affect the body, it affects the brain.
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Men with low testosterone, then I'm going get into the women, I'm not going to leave you
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alone, but it operates the same way.
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Brain fog, low motivation, anxiety or depression symptoms, poor confidence, and
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reduced resilience to stress.
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There's many different stress factors hitting us on a daily basis.
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And do we have resilience?
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Ask yourself that question.
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So optimized testosterone often improves focus, mood stability, emotional resilience, and the
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motivation to train, eat well, and sleep better.
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And I'll dig into that a little bit later into this episode, but this isn't about becoming
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someone new.
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It's about feeling like yourself again, of which you were.
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You need to go get that.
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So let's dig into the pro number three, which is recovery energy and overall vitality.
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When testosterone is optimized, not abused, it's a very clear term, not abused, patients
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often report better recovery from training, improved sleep quality, more consistent energy
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throughout the day, and less inflammation and joint pain.
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So this is why testosterone often becomes a force multiplier.
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What does that mean?
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It doesn't replace the good habits, it makes them work better.
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But I just don't want to stop there because I want to give you some cons.
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I want to be real here.
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I want to be transparent and why people get this wrong sometimes.
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So let's talk about the other side, and this is where people get into trouble.
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Testosterone has been abused.
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So let's be very clear.
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Testosterone got a bad reputation because it's been abused, not because it's inherently
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dangerous.
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Problems arise when doses are too high, you are not optimized.
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Labs aren't monitored.
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Estrogen is completely ignored, and lifestyle is neglected.
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Those are key contributors of how you abuse testosterone.
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So Peter T addresses this, the problem isn't testosterone, the problem is the irresponsible
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prescribing of it.
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So optimization is not bodybuilding.
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Optimization is not chasing numbers.
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Optimization is not, is precision medicine.
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And so that's where optimization comes into play.
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Hormones don't replace the basics.
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This is critical to think about.
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Testosterone is not the foundation of health.
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Your hormones are not the foundation of your health.
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The real hierarchy is resistance training, nutrition, sleep and stress management, then
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hormones.
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We are a product of our habits.
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James Clear said it the best, you don't rise to the level of your goals, you fall to the level
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of your systems, your habits.
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We are a makeup of our habits.
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So in that order, if you skip the basics and jump straight to hormones, trust me, you'll be
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gravely disappointed and potentially harmed in the effects.
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So hormones amplify effort, they do not create discipline.
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So let's get into this testosterone longevity and the bigger picture overall.
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When used correctly, testosterone may actually be protective long term.
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Emerging data has shown associates between optimized testosterone levels can reduce all
00:08:46
causes of mortality significantly.
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Cancer, diabetes, all those things.
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It can reduce if you have the proper habit structure along with hormone replacement
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therapy.
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Better cardiovascular outcomes, improved overall bone density, because it's able to
00:09:03
support more lean muscle mass, and the preservation of that muscle through the process
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of aging.
00:09:10
And here it goes, again, Peter Ottia, low testosterone is often not the disease, it's
00:09:14
just the signal.
00:09:16
Your body telling you, why do I have brain fog?
00:09:19
Why do I have a low libido?
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Why do I not feel like doing anything?
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And that signal becomes deeper and deeper and needs attention.
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But I know I focused a little bit on the testosterone side, but what about the ladies
00:09:35
HRT and the perimenopause phase?
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So I want to shift gears here a little bit because women are often way too overlooked in
00:09:43
this conversation.
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Ladies, this matters for you too.
00:09:47
Hormone replacement therapy, when done correctly, can be one of the most powerful
00:09:52
tools during perimenopause, menopause, and post menopause.
00:09:57
Symptoms like anxiety, poor sleep, brain fog, weight gain, mood swings, and then the loss of
00:10:02
drive or that identity are not things you just have to live with.
00:10:07
Peter, Tia and many longevity focused physicians now openly say HRT is a missing link
00:10:13
for women's health, bone health, and overall long term vitality.
00:10:18
And when used correctly, estrogen supports the brain, progesterone supports sleep and
00:10:26
calmness, reducing of stress.
00:10:29
Testosterone, yes even in women, supports strength, confidence, and overall metabolism.
00:10:35
This is not about vanity.
00:10:38
This is about the quality of life and longevity during one of the most hormonally challenging
00:10:44
stages of life.
00:10:46
So I want you to take that away, but here's the real takeaway: hormones are not magic.
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They are not dangerous when they are respected.
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Keyword, respected.
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And they certainly are not a shortcut.
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So when paired with resistance training, I wanna go back over this resistance training,
00:11:10
proper nutrition, smart monitoring, and individualized care, meaning this is doctor
00:11:17
directed, this is what you're dealing with a true professional, They can be one of the most
00:11:23
powerful tools we have to help you be strong, clear minded, and overall resilient.
00:11:33
So if you're curious about TOT, TRT, HRT, is this right for me?
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Or if you want real answers based on labs and science, I wanna invite you to go on to over to
00:11:46
a lesseefxhealth.com and book a consultation.
00:11:49
You know these are important things to stay educated on and really understand because as
00:11:56
our motto always goes, your health is in your hands and we truly believe that the power of
00:12:01
education allows you to live the life that you've always wanted to live.
00:12:07
So if you've gotten a little bit about a lot out of this episode you want to share it with
00:12:12
somebody please do this is how we help get the message out.
00:12:16
I want to thank you as always for tuning into Health Decoded.
00:12:19
I'm your host Matt Tack and remember as always your health is in your hands.
00:12:25
Thank you for tuning into Health Decoded where we break down the truth about all things health
00:12:31
and empower you to take charge of your well-being.
00:12:34
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00:12:40
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00:12:42
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00:12:47
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00:12:49
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00:12:55
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00:13:01
Until next time, stay curious, stay empowered, and remember, your health is in your hands.

