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We've actually entered an era of medicine that honestly would have seemed unimaginable.
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We now have tools that allow us to directly influence biological signals inside the body.
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And these tools fall into what many people call the world biohacking or regenerative medicine.
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The goal is not hacking the body.
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It's stimulating the body's natural healing mechanisms that already exist.
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Welcome to Health Decoded, your number one source for real health information with your
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host, doctor Alessi and Matt Tack.
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Hey there.
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Welcome back to Health Decoded.
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I'm your host, doctor Alessi.
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And today, we're gonna talk about something that I believe represents the true future of
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medicine.
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And it may not look exactly like what most people expect.
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When people think about the future of medicine, they often imagine more technology, more
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diagnostics, more drugs, machines.
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And technology absolutely plays an important role.
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We now have incredible tools like regenerative peptides, soft wave therapy, PEMF technology,
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advanced functional lab testing, precision nutraceuticals and vitamins.
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These are powerful innovations that allow us to stimulate healing pathways inside the body in
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ways that weren't possible twenty years ago.
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But here's the interesting thing, at the same time that medicine is becoming more high-tech,
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it's also rediscovering something incredibly old.
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Ancient healing traditions, practices like Ayurvedic medicine, traditional Chinese
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medicine, herbal medicine, breath work, circadian living, and energy based therapies.
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These are systems that have been around for thousands of years.
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And what's fascinating is that when we look at the science today, many of those ancient
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practices were actually describing real biological processes long before we had the
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technology to measure them.
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So the future of medicine may not be purely modern, and it may not be purely ancient.
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The future of medicine may actually be the intelligent integration of both.
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Today we're going to explore how these two worlds, modern regenerative medicine and
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ancient healing systems, can combine to create dramatic results in human health.
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So let's get right into it.
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First off, let's talk about what the problem is with modern medicine.
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So let's begin with an honest assessment of the current health care model.
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Modern Western medicine is an incredible achievement of human science.
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Nobody's taking that away.
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It has saved countless lives.
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And when it comes to acute care, it is arguably the most powerful medicine system humanity has
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ever developed.
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If someone experiences a traumatic injury or a severe infection or a heart attack or some type
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of surgical emergency, there's no question that modern medicine is extraordinary.
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The development of antibiotics, advanced surgical techniques, and trauma care has
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dramatically increased survival rates across the globe.
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For example, the mortality rate from a bacterial infection like pneumonia or sepsis
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used to be devastatingly high before antibiotics.
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Today, thanks to advances in pharmacology and emergency medicine, survival rates have
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improved.
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The same is true in trauma care.
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So according to research according to research published in the Journal of Trauma and Acute
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Care Surgery, improvements in trauma systems and surgical protocols have reduced mortality
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from severe injuries by thirty percent in many developed countries.
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So again, to be clear, modern medicine is incredibly powerful.
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But here's the key distinction.
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The modern health care model was designed primarily for one thing, to treat acute
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disease.
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It was not designed to solve or prevent chronic illness.
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And chronic illness is now the dominant health challenge of our time.
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According to the CDC, at the cent according to the Center for Disease Control and Prevention,
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roughly six out of ten adults in The United States now live with at least one chronic
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disease, and four out of ten live with two or more.
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These are things like metabolic syndrome, type two diabetes, autoimmune disease,
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cardiovascular disease, chronic fatigue syndromes, hormonal disorders, and
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neurodegenerative disease.
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These are not conditions that appear overnight.
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They slowly develop, often ten, twenty, or thirty years in the making, and they rarely
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have a single cause.
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Instead, they're gonna emerge from complex interactions between your genetics and your
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environment, your nutrition, your gut health, inflammation, stress, exposure to toxins, and
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the way that your sleep and circadian rhythm gets disrupted.
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In other words, these are systems problems, And systems problems require systems thinking.
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But historically, the dominant approach in modern medicine has been much more linear.
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The model often looks like this: patient develops a symptom, symptom leads to a
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diagnosis, diagnosis leads to a medication, and sometimes that medication works very well at
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reducing the symptom.
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But reducing a symptom is not always the same as restoring health.
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For example, if someone has high blood pressure, a medication may lower that number,
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but the medication does not necessarily address why the blood pressure rose in the first place.
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Was it from chronic inflammation or insulin resistance?
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Was it from stress physiology?
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Was it endothelial dysfunction or a nutrient deficiency?
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Those questions are often left unexplored.
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Another example is autoimmune disease.
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In autoimmune conditions, the immune system mistakenly attacks the body's own tissue.
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Conventional treatment often involves suppressing the immune system to reduce the
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symptoms.
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Sometimes that's necessary for short term, but suppression alone doesn't always answer the
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deeper question.
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Why did the immune system become dysregulated in the first place?
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Was it triggered by gut permeability, or a microbial imbalance, or a chronic infection?
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Was there some type of toxin, chronic stress, or deficiency in a nutrient?
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Those upstream drivers are rarely addressed within a symptom based model.
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And so this is where the conversation around functional medicine begins to emerge.
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Functional medicine asks a different set of questions.
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Instead of asking what drug treats this disease, it asks what physiological imbalance
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created this condition, and more importantly, what can we do to restore the body's natural
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regulatory systems?
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This approach is often described as looking at the terrain of the body.
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The terrain includes things like your gut microbiome, your immune system, your hormone
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signaling, mitochondrial energy production, detox pathways, and nervous system balance.
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When the terrain becomes disrupted, disease often follows.
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And what's fascinating is that this idea of biological terrain is not new.
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In fact, it's been central to many ancient medical traditions for thousands of years.
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Systems like Ayurveda and traditional Chinese medicine were built around the concept that
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health depends on maintaining balance within the body.
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They didn't frame it in terms of cytokines, mitochondrial function, or microbiome diversity
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because they didn't have the tools to measure that yet.
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But they were observing patterns.
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They recognized that your lifestyle, diet, stress, environmental exposure, they all shaped
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the body's internal balance.
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And they focused heavily on restoring that balance before disease became severe.
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In many ways, these ancient systems were practicing preventative systems medicine long
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before modern science had the technology to measure what was actually happening.
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So today we're beginning to see these worlds converge.
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Modern medicine and modern research is increasingly validating the importance of
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things like your microbiome health, inflammation, circadian rhythm alignment and
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nutrient sufficiency, as well as the physiology of stress, all of which were emphasized in
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traditional healing systems, and that realization led us to an important conclusion.
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The future of medicine may not lie exclusively in modern tech, and it may not lie exclusively
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in ancient tradition.
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Instead, I believe the most powerful approach may be the intelligent integration of both,
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using modern science to understand the biology while applying the wisdom of ancient systems
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that recognize the importance of balance, lifestyle, and daily health maintenance.
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And that intersection, where cutting edge regenerative therapies meet time tested healing
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principles, is exactly where medicine is headed next.
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So let's get into ancient medicine, thousands of years of observational biology, and how that
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has affected the way we approach things nowadays.
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So if modern medicine, as we said, is excelling at acute intervention but struggles with
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chronic disease, it's going to raise an interesting question.
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What systems of medicine were designed to manage long term health imbalance?
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When we look back through history, we find several traditions were built exactly for that
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purpose.
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Two of the most influential and two that I practice are Ayurvedic medicine, which
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originated back in India over three thousand years ago, and traditional Chinese medicine,
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which dates back more than twenty five hundred years.
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Now at first glance, these systems may seem completely different from modern Western
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medicine because they're gonna talk about concepts like qi or life energy, meridian
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pathways, doshas, yin and yang balance.
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And understandably, those concepts are abstract and can sound woo woo to most people.
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But when modern science began studying these practices more closely, something fascinating
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emerged.
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Many of these ancient frameworks were actually describing real biological processes just using
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a different language.
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So for example, take the practice of acupuncture.
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For centuries, acupuncture was explained through the movement of qi along meridian
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pathways.
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Modern research now shows that acupuncture can influence nervous system signaling,
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inflammation pathways, the release of endorphins, and blood flow regulation.
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And there's a review published in the Journal of Pain that found that acupuncture
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significantly reduces chronic pain conditions such as osteoarthritis, lower back pain
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compared to standard care.
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There's even functional MRI studies that have demonstrated that acupuncture can alter
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activity in the brain regions that are involved in pain perception.
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So another, awesome example is herbal medicine.
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Traditional Chinese medicine has used botanical compounds for thousands of years, many of which
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modern pharmacology has been based on.
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And so modern pharmacology has begun studying these herbs and identifying the compounds that
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influence physiological pathways.
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Great example, one that we use all the time, is berberine.
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Berberine is found in plants like coptus and goldenseal and has been shown in studies to
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significantly improve insulin sensitivity and blood sugar regulation.
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In fact, several studies found berberine to perform similarly, if not better, to the drug
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metformin in certain metabolic markers.
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Ayurvedic medicine offers another great example.
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It places an enormous emphasis on digestive health, something they refer to as agni or
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digestive fire.
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Modern medicine is now discovering that the gut microbiome plays a central role in immune
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regulation, inflammation, hormone metabolism, and brain function.
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And research published in Nature Reviews of Gastroenterology showed that disturbances in
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the gut microbiome are associated with conditions ranging from autoimmune disease to
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depression.
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So when Ayurvedic practitioners spent centuries focusing on digestion as the foundation of
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health, they were actually observing something very real, they just didn't yet have the tools
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to measure the gut microbiome.
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Another awesome principle that modern science has rediscovered is the importance of circadian
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rhythms.
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Traditional healing systems always long recommended aligning your daily routines with
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the natural cycles.
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Wake with the sunlight, eating during daylight hours, and sleeping shortly after sunset.
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Today, we know that the circadian rhythm can regulate hormones, metabolism, immune function,
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mitochondrial function.
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There is great research from the Salk Institute and Harvard Medical School that showed that
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circadian disruption, such as irregular sleep schedules or late night eating, significantly
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increases the risk of metabolic disease.
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So when we take a step back and look, something remarkable is aligned.
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Ancient medicine, through centuries of observation, recognized patterns that modern
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science is now beginning to understand through testing.
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And so these traditions were built around a central principle.
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Health is not the absence of disease.
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Health is the presence of balance within the body's systems.
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Maintaining that balance then requires daily practice that supports the body's natural and
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regulatory mechanisms.
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But while ancient medicine excelled at understanding patterns of health, it lacked
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what modern medicine excels at.
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Powerful technology.
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And that brings us to now the other side of this conversation.
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So now let's get into modern biohacking and regenerative medicine and the cool tech stuff
00:13:15
that everyone's so interested in nowadays.
00:13:17
But before we do that, let me pause for a quick message from one of our sponsors, and we'll be
00:13:22
right back.
00:13:23
Hey, busy professionals and parents.
00:13:26
Let me ask you something.
00:13:27
Do you need help with your low energy, stubborn weight, brain fog, gut issues, or hormones, but
00:13:34
you don't know where to start?
00:13:36
Well, you're not alone.
00:13:37
The biggest problem is that modern healthcare is designed to diagnose disease, but often
00:13:43
misses the dysfunction that begins years earlier as under the surface symptoms.
00:13:49
That's exactly why I created the functional medicine starter system.
00:13:54
This is a structured physician led process designed to uncover what is actually driving
00:13:59
your symptoms, whether it's rooted in gut health, metabolic function, inflammation,
00:14:04
nutrient status, or hormonal imbalance.
00:14:07
No guessing, no generic protocols, just real data and a clear plan.
00:14:12
So if you're tired of searching for answers, but you're not sure how to begin solving your
00:14:17
health issues, go to the link in the podcast show notes to learn more about the functional
00:14:21
medicine starter system.
00:14:23
Because once you have clarity, you can finally start to feel like yourself again.
00:14:28
Now let's get back to the episode.
00:14:31
Alright.
00:14:31
Welcome back.
00:14:32
So let's get into the other side of the coin here, modern biohacking, regenerative medicine,
00:14:38
high-tech interventions for influencing health.
00:14:42
And over the last two decades, we've actually entered an era of medicine that honestly would
00:14:47
have seemed unimaginable.
00:14:48
We now have tools that allow us to directly influence biological signals inside the body.
00:14:54
And these tools fall into what many people call the world of biohacking or regenerative
00:14:58
medicine, but the goal is not hacking the body, it's stimulating the body's natural healing
00:15:04
mechanisms that already exist.
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One of the most exciting developments is actually something called peptide therapy.
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And if you're not familiar, peptides are short chains of amino acids that act as signaling
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molecules throughout the body.
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Think of them as biological messengers.
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They're going to tell cells when to repair tissue, when to reduce inflammation, produce
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growth factors or growth hormone, or activate immune responses.
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Certain peptides have become particularly well known in regenerative medicine.
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For example, one of the most popular is BPC 157.
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This is a peptide originally derived from gastric proteins in the gut, has been studied
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for the ability to support the healing of tendons and ligaments and connective tissue.
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Animal studies in the Journal of Current Pharmaceutical Design and Peptides showed that
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BPC-one hundred fifty seven can accelerate healing in damaged muscle and tendon by
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enhancing angiogenesis, which is the formation of new blood vessels.
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Another awesome peptide is TB 500.
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This works by influencing protein called thymosin beta four, which plays a role in
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cellular migration and tissue repair.
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So these peptides aren't replacing your body's healing processes, your body is going to do
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that.
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They just amplify them and speed that process up.
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Then we have technology like soft wave therapy, something we work with a lot within our clinic,
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which is a form of acoustic wave therapy, similar to an ultrasound.
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Soft wave uses high energy sound waves to stimulate tissue repair.
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When these waves interact with the tissue, they create a biological response that is going to
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increase blood flow, increase stem cell activation, collagen production, and reduce
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inflammatory signaling.
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Clinical studies have also shown that acoustic wave therapy improves conditions such as
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plantar fasciitis, chronic tendon injuries, and joint pain.
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Another cool technology, something we use a lot as well, is PEMF or pulsed electromagnetic
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field therapy.
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So PEMF works by applying low frequency electromagnetic pulse to the body.
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These pulses, they influence cellular electrical activity and mitochondrial function.
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And there's research from the journal Bioelectromagnetics and Orthopedic Research
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shown PMF therapy improves bone healing, tissue regeneration, and inflammation reduction.
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In fact, PMF is FDA approved for bone fracture healing for the last decade.
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And what all these technologies have in common is that they aim to stimulate regenerative
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biology, so the body's ability to repair.
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They activate pathways that the body already possesses, but the critical point people miss
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is that they work best when the biological terrain is healthy.
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And so if someone has nutrient deficiencies, gut inflammation, metabolic dysfunction, they
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are having poor sleep or a high toxicity, a high burden of toxins in the body, their
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ability to respond to regenerative therapy is gonna be limited.
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So you can stimulate healing pathways, but if you lack the resources or the raw ingredients
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to execute those repairs, your progress will still be slow.
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This is often where we find that patients are missing when they're going through some type of
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healing journey.
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They have back pain, joint pain, knee pain, whatever it may be.
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They've been to chiropractors, physical therapists, all kind of stuff, massage therapy,
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and they get temporary relief but nothing's actually working.
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And that's because their internal system is not allowing their body to integrate that healing.
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And so the integration comes from using the wisdom of ancient systems to support the body's
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foundational balance, that's the internal, while using modern regenerative technology to
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accelerate that healing and recovery.
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When those two worlds come together, we see something remarkable.
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We move beyond treating disease and begin engineering resilience.
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And that is a term we use in our clinic all the time.
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We are trying to improve the body's resilience.
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How do we make it so that you don't need to do these things forever?
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Your body can then operate, manage, and do what it needs to do for a long period of time.
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And so the integration is where the future of medicine really lives, right?
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So now this is the most important idea of this entire episode, so if you take away nothing
00:19:31
else, if ancient medicine provides wisdom about balanced lifestyle and prevention, and modern
00:19:38
medicine provides powerful tools to stimulate healing and regeneration, then really the real
00:19:43
breakthrough happens when these two systems are combined.
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Because one each because each one solves a problem that the other can't.
00:19:52
Pause Kyle, let me redo that.
00:19:54
Because each one solves a problem that the other cannot solve alone.
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Ancient healing traditions are going to excel at creating the right environment for health,
00:20:04
focusing on things like sleep and circadian rhythm, breath and nervous system regulation,
00:20:10
nutritional and digestive strength, using herbal compounds that support your physiology,
00:20:16
movement practices, seasonal environmental alignment.
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In other words, they support what we call the biological terrain, the internal environment in
00:20:24
which your cells live and operate.
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If that terrain is healthy, healing happens more easily.
00:20:30
Think of it like this.
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You're trying to build a house or you're renovating a house, but the foundation, the the
00:20:36
ground on which that house is built on is not appropriate.
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It's there's dysfunction to it.
00:20:42
It's not healthy.
00:20:44
You need to you need to basically work down to the the bones, and you need to reset that.
00:20:48
You need to rebuild the foundation so that then your reno, your your build can be ideal.
00:20:55
Because if the terrain is inflamed or toxic or metabolically dysfunctional, healing becomes
00:21:00
difficult.
00:21:01
This concept is actually supported by a lot of research too.
00:21:04
And so, for example, I pulled this study published in Nature Reviews Immunology.
00:21:09
It showed that chronic systemic inflammation disrupts nearly every major biological system
00:21:15
in the body, including your hormones, your mitochondria, immune system, and tissue repair.
00:21:20
So even if we introduce powerful therapies, things like soft wave, peptides, if the terrain
00:21:26
is not prepared, they are not going to work as optimal.
00:21:29
And this is where ancient medicine has enormous value because ancient systems, you know, they
00:21:34
also had limitations.
00:21:36
They lacked the ability to intervene quickly and precisely when the body needed stronger
00:21:41
stimulation, and this is where then the modern regenerative medicine comes in.
00:21:45
So here's a real world example, right?
00:21:47
Imagine a patient dealing with chronic knee pain.
00:21:50
We see this all the time.
00:21:51
In a purely conventional model, the treatment pathway probably looks like this.
00:21:56
They have pain, so they get an anti inflammatory medication, maybe an injection,
00:22:01
they do some physical therapy, and they possibly have surgery.
00:22:04
But in an integrative model, the thinking becomes much broader.
00:22:08
First, I'm going ask some questions.
00:22:10
Number one, is there structural damage in the joint?
00:22:13
Number two, what is the inflammatory environment of the body?
00:22:16
Number three, what is the regenerative capacity of the tissue?
00:22:20
And number four: What lifestyle factors are possibly preventing healing?
00:22:25
Now in an integrative model the treatment might look like this: Softwave therapy to stimulate
00:22:30
tissue regeneration and stem cell activation.
00:22:33
PEMF therapy to improve mitochondrial function and cellular signaling.
00:22:38
Collagen and amino acid support to provide building blocks for connective tissue.
00:22:43
Anti inflammatory nutrition to reduce systemic inflammation.
00:22:47
Some powerful herbal compounds like curcumin or boswellia supporting that inflammatory balance,
00:22:53
and then movement and mobility practice to restore biomechanics.
00:22:57
Each of these interventions supports a different part of the healing process.
00:23:01
The technology stimulates that regeneration, whereas the lifestyle and nutritional practices
00:23:06
support the body's ability to execute that repair.
00:23:09
Together then, the effect becomes much more powerful.
00:23:13
Another example comes more in the let's think more on metabolic health.
00:23:17
Somebody with metabolic syndrome, maybe they have insulin resistance, chronic inflammation,
00:23:23
disrupted gut microbiome, poor sleep quality.
00:23:26
In the conventional model, treatment might involve medications for blood sugar or
00:23:30
cholesterol, but in an integrative model, we look at the entire system.
00:23:35
We would probably combine advanced lab testing to understand metabolic signaling, targeted
00:23:41
nutraceuticals to improve insulin sensitivity, gut restoration, circadian rhythm alignment,
00:23:48
resistance training to improve glucose metabolism, and in some cases we may even use
00:23:53
peptide therapies to support metabolic signaling and tissue repair.
00:23:57
When these approaches are combined, the body begins to move back toward metabolic stability.
00:24:02
What we often see in these cases is not just symptom relief, but a true shift in the
00:24:07
underlying physiology.
00:24:08
And we've seen it in our clinic, people go from type two diabetic diagnosed to non diagnosed.
00:24:15
And this is what I believe is the future of medicine.
00:24:17
It's going to look like this, not just pharmaceuticals, not just natural medicine, but
00:24:22
precise integration where we use the best available science from every discipline to
00:24:27
support the body's natural intelligence.
00:24:29
Because the human body is not a machine with replaceable parts, although some may think
00:24:34
that.
00:24:34
It's an incredibly complex biological ecosystem, And ecosystems thrive when the right
00:24:39
conditions are created.
00:24:41
The concept is sometimes referred to as systems medicine or integrative longevity medicine.
00:24:48
The goal is not simply to extend lifespan, the goal is to extend health span.
00:24:52
And this is where the mental shift needs to happen.
00:24:54
We don't just want to live longer if living longer means we're going to be in a chair and
00:24:58
indolent, but we want to be healthy longer.
00:25:01
Even if we don't live as long, can we live as well as we can into those older years?
00:25:07
And to help people maintain physical strength and metabolic resilience, cognitive clarity,
00:25:13
structural integrity, and emotional balance for as long as possible.
00:25:17
And so when we zoom out, what we can see is something remarkable happening in health care
00:25:22
right now, and I do believe that at Ascend Functional Health we are on the forefront of
00:25:28
this, because modern science is beginning to validate what ancient traditions already knew.
00:25:33
Health is not just about treating disease, it's about maintaining balance across systems of the
00:25:37
body.
00:25:39
And so what we do is we combine modern diagnostics, regenerative technology,
00:25:43
nutritional biochemistry with the ancient lifestyle principles.
00:25:48
We create a model of medicine that is far more powerful than either system alone.
00:25:53
And this is where we're headed.
00:25:54
In many ways, we're we're only at the beginning of this transition because the more we learn
00:25:58
about the human biology, the clearer it becomes that the body already possesses incredible
00:26:02
healing capabilities.
00:26:04
And we are learning every single day.
00:26:06
Our job is simply to remove the obstacles and provide the right signals.
00:26:10
When we do that consistently, the body often responds in ways that can be remarkable.
00:26:15
And so in closing, that was a lot of depth to that that episode, and and I hope this is
00:26:22
something that can help change the way that you're thinking, help give you a shift in your
00:26:27
mindset as to how you approach your health and your balance of your systems.
00:26:31
And if we zoom out and look at the trajectory over the next twenty or thirty years, the
00:26:36
systems that will dominate are those that combine advanced diagnostics, regenerative
00:26:41
tech, and personalized nutrition with the ancient healing principles.
00:26:45
And not just because it's trendy, but because it works.
00:26:48
And the future of medicine is not just about treating your disease, but again, about
00:26:52
engineering resilience, helping your body maintain strength, clarity, musculoskeletal
00:26:59
integrity, and immune intelligence for as long as possible.
00:27:01
So again, I wanna thank you so much for joining me on this episode of Health Decoded.
00:27:06
If you find value in this episode or any of our episodes, please follow, like the show,
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subscribe, and share this with someone who's interested because that's how we get the
00:27:17
message out, and that's how we're able to help more people take back control of their health.
00:27:21
If you wanna learn more about our functional and regenerative medicine programs, you can
00:27:26
visit our website, alessifunctionalhealth.com, schedule consultation, check out our
00:27:31
newsletter, any of our resources that we have, and make sure you subscribe to the show so you
00:27:35
never miss anything.
00:27:37
So thanks again for tuning in to Health Decoded.
00:27:40
I'm doctor Lessie, and I'll see you on the next one.
00:27:44
Thank you for tuning in to Health Decoded, where we break down the truth about all things
00:27:48
health and empower you to take charge of your well-being.
00:27:52
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00:27:57
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00:27:59
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00:28:07
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00:28:12
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00:28:18
Until next time.
00:28:19
Stay curious, stay empowered, and remember, your health is in your hands.